Studies on the host-range mutation in T2 bacteriophage

Lysogeny and bacteriophage host range within the Burkholderia cepacia complex.

The Burkholderia cepacia complex comprises a group of nine closely related species that have emerged as life-threatening pulmonary pathogens in immunocompromised patients, particularly individuals with cystic fibrosis or chronic granulomatous disease. Attempts to explain the genomic plasticity, adaptability and virulence of the complex have paid little attention to bacteriophages, particularly ...

Epidemiological Studies on Ruman Brucellosis in Iran and the Identification by Bacteriophage

Frequency and Fitness Consequences of Bacteriophage Φ6 Host Range Mutations

Viruses readily mutate and gain the ability to infect novel hosts, but few data are available regarding the number of possible host range-expanding mutations allowing infection of any given novel host, and the fitness consequences of these mutations on original and novel hosts. To gain insight into the process of host range expansion, we isolated and sequenced 69 independent mutants of the dsRN...

Studies on Bacteriophage and Metabolic Identification of Brucella Strains

Chemical analysis of the T2 bacteriophage and its host, Escherichia coli (strain B).

A particulate component of characteristic morphology and behaving biologically as the Tz bacteriophage of Escherichiu coli (strain B) has been isolated by centrifugation (1) from lysates of the host grown in nutrient broth and in synthetic saline medium. The purified bacteriophage concentrates exhibited a high degree of homogeneity with respect to particle kind in electron micrographs (1, 2), a...